May update: Pods, Phoenix experiment, Monthly themes

Hi everyone!

April has been a whirlwind, and I’ve got some exciting updates about where we are and what's ahead for the Phoenix Community.

1. Monthly Pods and Introducing Fenix

By now, members of The Phoenix Community should have been matched into your monthly pods. If you intended to join a pod but haven't yet been matched, please send me a note.

Pod matching is one of our community’s core features: each month, members are grouped into small peer-support teams (called pods) based on shared goals, lifestyle, and genetic context. These pods are where real support, accountability, and shared experimentation happen—so you’re never going at this alone.

Matching took a bit longer this month because we've welcomed someone new: Fenix, our AI support agent. Fenix will enhance our pod matching by analyzing inputs from your application forms, onboarding information, and monthly check-ins.
Soon, she’ll also consider community conversations to better understand your needs. Additionally, Fenix will play a key role in the upcoming Phoenix Experiment Module.

2. Monthly Themes: DNA & Genetics (May)

We're excited to introduce a new community rhythm: Monthly Themes. Each month we'll explore one important area in depth to support ApoE4 prevention and healthy longevity.

Our inaugural theme for May is DNA & Genetics. We'll examine what your genetic code reveals, how to interpret risk reports effectively, and identify additional genetic markers beyond APOE that influence inflammation, detoxification, metabolism, and more.

Expect curated posts, expert-led live sessions, vibrant discussions, and opportunities to test personalized interventions aligned with your genetic makeup.

3. Cutting-Edge Research from AAIC & ADPD

I’ve been slightly procrastinating on these updates—filming and editing videos aren't my strengths—but I’m embracing the challenge as a valuable skill and brain-sharpening exercise.

Starting this month, look forward to new YouTube videos summarizing key insights from the AAIC (Alzheimer’s Association International Conference) and ADPD (International Conference on Alzheimer’s and Parkinson’s Diseases).

These sessions are genuinely fascinating, and some of the key topics you'll learn about include:

• How APOE4 reshapes microglia and disrupts blood vessels in the brain.

• Innovative interventions targeting cholesterol metabolism and inflammation.

• New insights into ancestry-specific genetic risks.

• Emerging therapies such as antisense oligonucleotides to lower APOE4.

• The growing role of precision medicine in personalized prevention strategies.

Each video explains complex science clearly, always concluding with actionable takeaways specifically tailored for ApoE4 carriers.

4. The Phoenix Experiment Module

I’ve been collaborating with leading global researchers to design this vital new module.

The Phoenix Experiment Module represents the first-ever continuous, community-driven, N-of-Many trial network dedicated exclusively to APOE4 carriers determined to overcome Alzheimer's disease.

This innovative system helps you discover, personalize, and optimize your unique protocol for maximizing cognitive health and longevity. It analyzes real-world data from biomarkers, wearables, cognitive assessments, and lifestyle factors, dynamically adapting to create your personalized longevity blueprint.

Why is this crucial?

Traditional clinical trials often take years and may never happen for non-patentable interventions such as nutrition or stress reduction. Standard medical advice tends to rely on generic, one-size-fits-all recommendations, which aren’t optimal for ApoE4 carriers, given the highly individual nature of genetic risk.

The Phoenix Experiment flips the conventional model. Instead of passively waiting for answers, we actively generate them—together. Members run structured experiments, track outcomes, and collectively refine the system, enabling rapid, precise identification of effective interventions.

Stay tuned for more details soon—this initiative is my primary focus, and with input from world-class researchers that are joining our scientific board like Pr. Yadong Huang from UCSF / Gladstone Institute, we aim to make it robust and impactful.

5. Community Growth

I'm thrilled to announce that we've been doubling our size every month!

Why does this matter?

A larger community means:

• Improved pod matching accuracy.

• Greater access to top researchers and academic experts for live Q&A sessions.

• Enhanced negotiation power for perks and partnerships.

• Richer, more meaningful data for the Phoenix Experiment Module.

The more we grow, the stronger and more effective we become in our shared mission.

If you're reading this newsletter and haven’t yet joined the Phoenix Community, you can apply here. I personally review all applications—mention that you're a newsletter subscriber, and I’ll be sure to give your application a bit of extra love!

If you have ideas to help accelerate our community growth or know someone who would benefit from joining us, please reach out—I’d love your help spreading the word.

That’s it for our May update! Thank you for being part of The Phoenix Community’s journey—I hope you’re as excited about what's next as I am.