MCT Oil, GLP-1, lowering LDL, HSV-1, Keto, Fibers and more!

Hi friends,

May was so rich in discussions!!

We had a fascinating Live Q&A with our Phoenix Founding Member Pr. Margit Burmeister on the topic of DNA and Genetics. Pr. Burmeister has spent decades uncovering the genetic roots of neurological and psychiatric disorders.
She brings deep expertise in brain health, gene-environment interactions, and neurodegeneration—and she also happens to be an ApoE2/4 carrier herself, giving her a uniquely personal perspective.

Our members were matched in their monthly pods (grouping ApoE4 carriers that share similar health profile — genetics, environment, habits, goals) because there is no one-size fits-all answers when it comes to your health.
What works for people similar to you has a much higher chance to work for you too!

May Pods Highlights:

• Lipid Lowering League – Cholesterol

• Resilience Circle – Stress

• Deep Sleep Guild – Sleep

• Quant Crew – Biohack

• Agility Alliance – Sports

As our community continues to double in size each month, we're now exploring more and more fascinating topics.
Below, you’ll find a preview of some of the threads started by our members.

May Topics Highlights:

Supplements, Nutrition, and Medication

• Would One Meal a Day be cognitive protective? Why?

• Coconut Oil

• Optimal macro mix for ApoE4s: Protein %, Carb %, Fat %

• Help needed determining and tracking macros for ketosis.

• Acetyl L carnitine and high TMAO

• Ninja Creami and making ice creams

• Chobani vs Fage

• Modified Citrus Pectin (MCP) and stress reduction

• Soluble fiber – anti-inflammatory, modulates the gut microbiome and more?

• Microdosing Semaglutide

• Testosterone Therapy for Males

• Lithium Microdose

Sports, Sleep, and Stress management

• Swimming seems to have some additional benefits compared to other sports

• Outsized effect interventions for brain clarity / avoiding brain fog

Biomarkers, Tracking, Monitoring

• Proof that diet and Strategy do Work for Apoe4! I lowered my LDL 76 points!

• Updated cholesterol and a1C

• Cholesterol Balance Test Hyper absorb or Hyper produce

Toxins, Pathogens, Heavy metals

• HSV1 and AD / Dementia risk

Tech and Medical devices

• Cognitive training apps

• Ketone Monitoring

• Red Light Therapy

Genetics

• Sequencing.com Kit is processing

• Detailed sequencing reports, premium plan

• How many rs protective variants are there?

Research

• The use of GLP-1 s for dementia prevention.

• IntellxxDNA report and worksheet

• Stopping inflammation

• Ezetimibe for prevention

• Small human pilot study shows 20g creatine supplementation and improved brain energetics

• Untitled post

• Evidence Linking SGLT2 Inhibitors to Alzheimer’s/Dementia Prevention

• 7 APOE4 Breakthroughs That Could Delay Alzheimer’s, from the Alzheimer’s Association International Conference on APOE and Lipid Biology (March 2025)

• Melatonin: I am receiving a newsletter called Genetic Life Hacks. This article on Melatonin is very interesting. The body’s ability to produce Melatonin is influenced by circadian rhythm. Worth implementing.

• Alzheimer’s and circadian rhythm.

• Study showing ApoE4s got better cognition after … HIGH GI and saturated fat meal

As always, thank you for being part of this mission to help all ApoE4s beat the odds and defeat Alzheimer’s. 🧡

Kevin