My Framework for Choosing Which Interventions Are Worth It

Hi friends,

Most people waste time on the wrong interventions.
They chase the latest supplement, run themselves into burnout, or cut foods they love—only to see barely any change.
And as an ApoE4 carrier, that’s not just frustrating—it’s risky.

What you need isn’t more advice.
You need a system: a clear way to figure out what actually works for you.

When you do, everything gets easier:
✅ You’ll stop second-guessing your choices
✅ You’ll focus your energy where it matters
✅ You’ll build a protocol that fits your life, and helps protect your brain

This post will show you the exact framework I use to do that.
No guesswork. No hype. Just what works, for you.

Before we dive in, there are two key truths we need to keep in mind:

1) You still want to enjoy your life

Our goal is not to obsess over Alzheimer’s risk or let ApoE4 define your life.
We all want to live fully, stay sharp—and enjoy the ride.

BUT, you’ll probably end up doing a few interventions daily for the rest of your life (like taking a couple supplements or begrudgingly skipping the cheese platter).
So it makes sense to invest a little time upfront to find the protocol that works for you—instead of leaving it to chance.

2) You are unique, so you protocol is too

Let’s take a simple example:
Say you want to reduce LDL-C / ApoB (one of the key levers for ApoE4 carriers). You might consider:

• ❌ Cutting steak and cheese from your diet

• 🏃‍♂️ Running 30km per week

• 💊 Taking ezetimibe

Each one sounds reasonable on paper, but the actual impact? 
That’s completely personal and depends on your genes, habits, environment etc.

If you’re a hyper-absorber of cholesterol, cutting steak and cheese and taking Ezetimibe might drop your LDL-C significantly. But if you are not, the impact might not be that big.

And then there’s the part most people ignore:
Ease of implementation (i.e. what’s the effort needed for you to implement it)

Running 30km a week might feel like therapy for some, and absolute torture for others.

That’s why there’s no one-size-fits-all answer.
You need a way to map out your interventions in a 2×2 matrix like this (yes I used to work in consulting, why do you ask?)

The vertical axis is the hardest part to get right—measuring impact.
That’s where The Phoenix Community comes in: we help you run structured self-experiments, track real-world results, and use predictive tools (like AI, big data, and digital twin models) to identify which interventions actually make a difference.
You can apply to join us here.

And if that sounds too complex—don’t worry:
We’re building an AI-powered app that will simplify this entire process.
You’ll simply follow a guided protocol, and the AI will help you prioritize interventions based on your own results—and what’s worked for other members with similar health profiles.

I actually have a VERY exciting announcement about this soon, make sure you are subscribed to our newsletter to not miss it!

All right let’s go back to our 2×2 matrix

Once you’ve plotted your interventions, you can start to prioritize.

The chart breaks down into 4 clear quadrants:

🟢 Top right = Keepers
High impact, easy to do.
These are your no-brainers. They stay in your routine—forever if needed.

🔴 Bottom left = Drop them
Low impact, hard to do.
These are energy drains. They go straight to the bin.

🟡 Diagonal zone = Maybes
Here’s where things get flexible.
You might go for a quick win from the bottom right quadrant: something easy but low-impact.
Or, if you’re feeling especially committed (new year, new you mode), you might add a hard but high-impact intervention to the mix from the top left quadrant.

So here’s the bottom line: Not everything is worth doing.
And not everything that works for someone else will work for you.

If you're serious about protecting your brain, you need more than willpower.
You need clarity.
A system.
A way to track what works, ignore what doesn’t, and build a protocol that fits you.

That’s what we do inside The Phoenix.

We don’t guess.
We test.
We learn.
And we do it together.

Because when you’re facing ApoE4, doing “what everyone else does” just isn’t enough.

You need precision. You need support. You need a plan.
And with the right system in place,
You won’t just survive ApoE4.
You’ll thrive with it.